Salivary Glands of Cockroach

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The effects of serotonin and dopamine on salivary secretion by isolated cockroach salivary glands

We have studied the effects of 3-hydroxytyramine (dopamine) and 5-hydroxytryptamine (serotonin) on (1) the rates of salivation from isolated salivary glands of the cockroach Periplaneta americana, (2) the protein content of the saliva, and (3) the ultrastructure of the salivary gland epithelium. The rates of neurotransmitter-induced salivation varied in a dose-dependent manner within the concen...

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Salivary Glands

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Salivary Glands

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Dopaminergic and serotonergic innervation of cockroach salivary glands: distribution and morphology of synapses and release sites.

The paired salivary glands in the cockroach are composed of acini with ion-transporting peripheral P-cells and protein-secreting central C-cells, and a duct system for the modification of the primary saliva. Secretory activity is controlled by serotonergic and dopaminergic neurons, whose axons form a dense plexus on the glands. The spatial relationship of release sites for serotonin and dopamin...

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ژورنال

عنوان ژورنال: Nature

سال: 1874

ISSN: 0028-0836,1476-4687

DOI: 10.1038/010439c0